ISO-80隔離式生物放大器, 附主動式探針
Extracellular Amplifier with Active Probe
型號： ISO-80

• 監控細胞外神經動作電位。
• 用於細胞標記、刺激或電極清潔。
• 應用範圍包含測量肌電圖EMG、腦波圖EEG、細胞外和動作電位。

特色

改良的ISO-80提供低噪音AC耦合放大與優越的紀錄性能，用於監控體外(in vitro)和活體動物中的細胞外神經動作電位。ISO-80內含整合了電極阻抗測試功能和恆定電流刺激器的遠端操控headstage (1mm cable)。恆定電流刺激器可用於細胞標記、刺激或電極清潔。典型應用包含測量肌電圖EMG、腦波圖EEG、細胞外和體外(in vitro)或體內(in vivo)的動作電位。ISO-80系統為DC隔絕待測物，且採用電磁屏蔽技術之狀態，以增進噪音抑制。此放大器採用高通和低通濾波，帶增益100~10,000。最低低通設置為5Hz，upper passband為10kHz。

啟動套組包含：

ISO-80內含一個啟動套組，內附下列用於基本金屬電極電生理研究用之配件：2個#CBL102 cable(2m BNC轉接3.5插孔)、2個#5469適配器(mini-banana to 0.031 skt)、2個#13388適配器(mini-banana to 2mm skt)、1個#2034微型香蕉插頭(紅色)、2個#2035微型香蕉插頭可焊接turrent、1個EP1銀/氯化銀小球、2個M3301EH電極夾持器、1袋#5470線纜。

規格

搭配各式選配，可有多種應用。以下您可以看到2種設置。

金屬電極的差分應用

在此配置中，金屬電極搭配差分放大器使用，下圖使用DAM80，但是您也可以簡單換成DAM50(搭配#5489)、ISO-DAM8A(搭配#74040)或ISO-80。

Mutliple applications are available with a variety of options. Here you can see two setups.

Differential Applications for Metal Electrodes

In this setup, metal electrodes are used with a differential amplifier. In this setup, a DAM80 is shown, but you could easily substitute a DAM50 (with 5489), ISO-DAM8A (with 74040) or ISO-80.

利用玻璃為電極的細胞外應用

在罕見情 形下當使用細胞外放大器搭配玻璃，你可以採用下圖所示配置。在此設置中採用DAM80，但您也可以簡單的替換成ISO-DAM8A(搭配#74040)或 ISO-80。同樣的，此設置採用#2505握柄 (1/4"-6.3mm)，但是若您的顯微操縱器較小，可能需要使用#5444握柄(3/16"-4.8mm)。圖中配置採用MEH7W-10，但是任何玻璃尺寸的MEH7W均可使用。(MEH7W-10是1.0mm玻璃、MEH7W-12為1.2mm玻璃、MEH7W-15為1.5mm玻璃、MEH7W-20為2.0mm玻璃) 圖中的EP2用於接地。

單端型應用時，在黑色連接器插座上的#2033線纜適配器可連接至#3294電纜。尖端依您的需求而定。圖中建議使用#TIP1TW1。注意，下圖未顯示出玻璃。

Extracellular Applications Utilizing Glass Microelectrodes

For rare instances when using extracellular amplifiers with glass, you could use the setup shown below. In this setup, a DAM80 is shown, but you could easily substitute an ISO-DAM8A (with 74040) or ISO-80. Likewise, this setup shows the 2505 handle (1/4" - 6.3mm), but if you have a smaller micromanipulator, you may need the 5444 handle (3/16" - 4.8mm). In this illustration, MEH7W-10 is used, but any glass-size MEH7W could be used. (MEH7W-10 is 1.0mm glass, MEH7W-12 is 1.2mm glass, MEH7W-15 is 1.5mm glass and MEH7W-20 is 2.0mm glass.) EP2 is used for grounding in the illustration.

For single-ended applications, however, a 2033 wire adapter on the black connector socket can be connected to the 3294 cable. The tip used depends on your specific needs. In the illustration, TIP1TW1 was suggested. NOTE that the glass is not shown in the illustration below.

Features

The improved ISO-80 provides low noise AC coupled amplification and offers excellent recording performance for monitoring extracellular nerve action potentials in vitro and in living animals. The ISO-80 is provided with a remote headstage (1 m cable) which incorporates an electrode impedance test function and a constant current stimulator. The constant current stimulator can be used for cell marking, stimulation or electrode cleaning. Typical applications include measuring EMG, EEG, extracellular and action potentials in vitro or in vivo. The ISO-80 system is DC isolated from the subject ground and employs state of the art electro-magnetic shielding for improved noise rejection. The amplifier employs both high pass and low pass filtering with gain from 100 to 10,000. The lowest low-pass setting is 5Hz and the upper passband is 10 kHz.

Start-up kit included

Included with the ISO-80 is a Startup Kit containing the following accessories needed for basic metal electrode electrophysiology research: two CBL102 Cable, BNC-to-3.5mm plug, 6 ft (2m), two 5469 Adapter, mini-banana to 0.031 skt, two 13388 Adapter, mini-banana to 2mm skt, one 3294 Cable, ground clip to wire (3 ft), one 2033 Mini-banana plug (black), one 2034 Mini-banana plug (red), two 2035 Mini-banana plug solderable turrent, one EP1 Ag/AgCl pellet (70 mm wire) 1mm diam x 2.5 mm long, two M3301EH Electrode Holder, 14cm, and one package of four 5470 0.031-inch jack on 12-inch wire.