Okamoto 1963 from outbred Wistar Kyoto rats. Bred from a male with mild hypertension, mated with a female with high blood pressure. Brother x sister mating with continued selection for high blood pressure (Okamoto 1969, Okamoto et al 1972). Spontaneously Hypertensive Rat
Strain characteristics
Hypertension
Breeding Conditions
Good breeding performance. Sib mating.
Genotyping
References
Okamoto K., Aoki K.
Development of a strain of spontaneously hypertensive rats
Jpn. Circ. J. 27: 282-293, 1963