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Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  black hooded (a,B,C,h) or brown hooded ( a,b,C,h)
Inbred Generations  F20+18 (09.5.29)
Usage Restrictions  
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability  
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected Lepr: leptin receptor
Origin A inbred strain from Zucker-fatty rats which were introduced to Takeda Chemical Industries in 1980.
Strain characteristics An autosomal recessive mutation fatty (fa) was caused of the missense mutation of the Lepr gene.
Breeding Conditions Maintained by crossing heterozygotes of the Lepr locus.
Genotyping PCR-RFLP
References  
Additional strain information KZ-Leprfa   

 
 
 
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