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Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  
Inbred Generations  N8F46
Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT must agree on collaborative research with the DEPOSITOR. Any form of publications of data resulting from the use of the BIOROGICAL RESOURCE require co-authorship. This condition is NOT limited to two-year period after deposition.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability  
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected Atp7b: ATPase, Cu++ transporting, beta polypeptide
Origin A congenic strain produced by 8 generation backcrosses to WKAH strain in 1989.
Strain characteristics hepatitis, hepatoma
Breeding Conditions Good breeding performance.
Genotyping  
References Minami T, Kaneda S, Otsuka T, Jiao Z, Suzuki Y, Yamada T, Matsumoto K, Izumi K.
Role of Atp7b gene in spontaneous and N-diethylnitrosamine-induced carcinogenesis in a new congenic strain, WKAH.C-Atp7b rats.
Jpn J Cancer Res. 2001 Aug;92(8):841-7.
Additional strain information WKAH   

 
 
 
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