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Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  
Inbred Generations  F25 (2004)
Usage Restrictions  
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability    
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected  
Origin The LEXF/FXLE RI strain set has been established by Shisa et al at Saitama Cancer Center Research Institute since 1985. This RI set consists of 34 RI strains derived by reciprocal crossing of LE/Stm (NBRP No.139) and F344/Stm (NBRP No.140).
Strain characteristics The RI strains are useful genetic tool in gene mapping and analysis of complicated trait genetic diseases.
Breeding Conditions Good breeding performance. Sib mating.
Genotyping  
References Shisa H, Lu L, Katoh H, Kawarai A, Tanuma J, Matsushima Y, Hiai H.
The LEXF: a new set of rat recombinant inbred strains between LE/Stm and F344.
Mamm Genome. 1997 May;8(5):324-7.

Lu LM, Shisa H, Tanuma J, Hiai H.
Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis.
Br J Cancer. 1999 May;80(5-6):855-61.

Voigt B, Kuramoto T, Mashimo T, Tsurumi T, Sasaki Y, Hokao R, Serikawa T.
Evaluation of LEXF/FXLE rat recombinant inbred strains for the genetic dissection of complex traits.
Physiol Genomics. 2008 Feb 19;32(3):335-42.
Additional strain information    

 
 
 
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