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Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  tan hooded (a,B,C,h,r)
Inbred Generations  F86+2+13 (09.5.29)
Usage Restrictions  
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability    
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected  
Origin The LE/Stm rats were introduced into Saitama Cancer Center Research Institute in 1969 from a closed colony of Long Evans rats maintained in the Ben May Laboratory for Cancer Research, University of Chicago. A mutant with red-eyed dilution was found in 1970 in the Long-Evans colony, and the mutation was fixed by selective mating. Thereafter, they were maintained by sister-brother mating more than F50.
Strain characteristics A parental strain of LEXF/FXLE RI strains (NBRP No.0105-0138).
Breeding Conditions Good breeding performance. Sib mating.
Genotyping  
References Shisa H, Lu L, Katoh H, Kawarai A, Tanuma J, Matsushima Y, Hiai H.
The LEXF: a new set of rat recombinant inbred strains between LE/Stm and F344.
Mamm Genome. 1997 May;8(5):324-7.

Lu LM, Shisa H, Tanuma J, Hiai H.
Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis.
Br J Cancer. 1999 May;80(5-6):855-61.
Additional strain information    

 
 
 
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