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閉鎖群 Closed Colony
 
遠交系大鼠 Outbred Rat
 
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日本實驗大鼠、小鼠
 
疾病模式動物
 
 

Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  albino (c)
Inbred Generations  F11 (09.5.29)
Usage Restrictions  The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability    
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 
 Control Strain  Marker Strain
Gene Affected GFP: Green Fluorescent Protein, jellyfish
Origin This strain was established at YS institute and maintained at PhoenixBio Co., Ltd. and Jichi Medical School. This transgenic rat was originated from Crlj:WI strain. (10.5.25)
Strain characteristics This transgenic strain expresses the enhanced green fluorescent protein (EGFP) ubiquitously driven by CAG promoter.
Breeding Conditions Good breeding performance.
Genotyping Hakamata Y et al., Biochem Biophys Res Commun 2001, 286:779-85
Sense 5'-CCTACGGCAAGCTGACCCTGAAGTT-3' Anti-sense 5'-AGGACCATGTGATCGCGCTTCTCGT-3'"
References Green fluorescent protein-transgenic rat: a tool for organ transplantation research.
Hakamata Y, Tahara K, Uchida H, Sakuma Y, Nakamura M, Kume A, Murakami T, Takahashi M, Takahashi R, Hirabayashi M, Ueda M, Miyoshi I, Kasai N, Kobayashi E.
Biochem Biophys Res Commun. 2001 Aug 31;286(4):779-85.

Offspring derived from intracytoplasmic injection of transgenic rat sperm.
Hirabayash M, Kato M, Aoto T, Sekimoto A, Ueda M, Miyoshi I, Kasai N, Hochi S.
Transgenic Res. 2002 Apr;11(2):221-8.

Lympho-myeloid chimerism achieved by spleen graft of green fluorescent protein transgenic rat in a combined pancreas transplantation model (TI03-029).
Sakuma Y, Sato Y, Inoue S, Kaneko T, Hakamata Y, Takahashi M, Murakami T, Kobayashi E.
Transpl Immunol. 2004 Jan;12(2):115-22.


Morphologic characterization of green fluorescent protein in embryonic, neonatal, and adult transgenic rats.
Takeuchi K, Sereemaspun A, Inagaki T, Hakamata Y, Kaneko T, Murakami T, Takahashi M, Kobayashi E, Ookawara S.
Anat Rec A Discov Mol Cell Evol Biol. 2003 Oct;274(2):883-6.

Long-lasting donor passenger leukocytes after hepatic and intestinal transplantation in rats.
Inoue S, Tahara K, Kaneko T, Ajiki T, Takeda S, Sato Y, Hakamata Y, Murakami T, Takahashi M, Kaneko M, Kobayashi E.
Transpl Immunol. 2004 Jan;12(2):123-31.
Additional strain information Wistar   

 
 
 
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