From ACI/Pas stock in Institute Pasteur, France. After 1998 introduced to Kyoto University, F344/NSlc backgrund congenic rats were established at Kyoto University.
Strain characteristics
short tail, neurologic disorder similar to dreher mouse, Mutation at the Lmx1a locus
Breeding Conditions
Heterozygtes qc/+ are backcorssed with F344/NSlc. Maintained in heterozygous condition.
Genotyping
Using markers linked with qc locus.
References
Kuwamura, M., Muraguchi, T., Matsui, T., Ueno, M., Takenaka, S., Yamate, J., Kotani, T., Kuramoto, T., Guenet, J-L., Kitada, K., Serikawa, T.
Mutation at the Lmx1a locus provokes aberrant brain development in the rat.
Brain Res Dev Brain Res 155(2):99-106, 2005