Preservation Status: |
Embryo Sperm Living Animals |
|
|
Coat Color |
cinnamon-like (A,B,C,D,r) |
Inbred Generations |
F94+13 (09.5.29) |
Usage Restrictions |
|
Genetic Status |
|
Comercial Availability |
|
|
Research Category |
|
Gene Affected |
Atp7b: ATPase, Cu++ transporting, beta polypeptide, Ptprk: protein tyrosine phosphatase, receptor type, K |
Origin |
Kobe university→Hokkaido University, Laboratory of Experimental Animal Science(Hok) 1975→Hokkaido University, Center for Experimental Plants & Animals(Hok) 1982, F20 |
Strain characteristics |
Developed at Hokkaido University, a model of Wilson disease, carries a mutation causing fulminant hepatitis and jaundice at about four months of age. |
Breeding Conditions |
Good breeding performance. Sib-mating. |
Genotyping |
|
References |
Rat News Letter 14: 4-6, 1985
J. Hereditary 78: 361-365, 1987
The LEC Rat, Springer Verlag, Tokyo, 1991 |
Additional strain information |
LEC |