The recipient of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT must agree on collaborative research with the DEPOSITOR. Any form of publications of data resulting from the use of the BIOROGICAL RESOURCE require co-authorship. This condition is NOT limited to two-year period after deposition.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
Ptprk: protein tyrosine phosphatase, receptor type, K, extracellular region
Origin
A congenic strain produced by 8 generation backcrosses to WKAH strain in 1989.
Strain characteristics
a defect of T cell maturation
Breeding Conditions
Good breeding performance.
Genotyping
References
Chai JG, Sakai T, Hisaeda H, Nagasawa H, Yasutomo K, Furukawa A, Ishikawa H, Maekawa Y, Uehara H, Izumi K, Matsumoto K, Himeno K. Development of functional rat-derived T cells in SCID mice engrafted with the fetal thymus of LEC rats which are defective in CD4+ T cells. Microbiol Immunol. 1996;40(9):659-64.