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Preservation Status:   Embryo        Sperm       Living Animals
Coat Color  albino (c)
Inbred Generations  F101+11 (09.5.29)
Usage Restrictions  In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genetic Status
 Inbred  Segregating  Congenic  Consomic  Recombinant
 Coisogenic  Spont. Mutant  Transgene  Ind. Mutant  Category Other 
Comercial Availability    
Research Category
 Diabetes Obesity  Neurobiology  Ophthalmology  Dentistry  Cardio Hypertension
 Cancer  Metabolism  Otorhinology  Immunology  Infectious
 Osteosis  Internal Organ  Dermatology  Reproduction  Development
 Behavior  Hematology  Urology  Pharmacology  Research Area Others 骨格筋萎縮
 Control Strain  Marker Strain
Gene Affected Actr3: ARP3 actin-related protein 3 homolog (yeast)
Origin Buffalo
Strain characteristics hymoma, muscle atrophy, and nephrosis
Breeding Conditions Sib mating.
Genotyping  
References Matsuyama, M., Nagayo, T.: Proc, Jpn.
Cancer Assoc., 36th Annu. meet., 30, 1977.

Nakamura T, Oite T, Shimizu F, Matsuyama M, Kazama T, Koda Y, Arakawa M.
Sclerotic lesions in the glomeruli of Buffalo/Mna rats.
Nephron. 1986;43(1):50-5

Kato F, Watanabe M.
Motor dysfunction in spontaneous thymoma rats, Buffalo/Mna.
J Pharmacobiodyn. 1982 Sep;5(9):727-33

Matsuyama M, Suzuki H, Yamada S, Ito M, Nagayo T.
Ultrastructure of spontaneous and urethan-induced thymomas in buffalo rats.
Cancer Res. 1975 Oct;35(10):2771-9

Oyabu A, Higo K, Ye C, Amo H, Saito M, Yagyu S, Morita H, Maeda K, Serikawa T, Takahashi M, Matsuyama M.
Genetic mapping of the thymoma susceptible locus, Tsr1, in BUF/Mna rats.
J Natl Cancer Inst. 1999 Feb 3;91(3):279-82

Murakumo Y, Takahashi M, Sharma N, Arakawa A, Saito M, Amo H, Matsuyama M.
Mapping of two genetic loci, Ten-1 and Ten-2, associated with thymus enlargement in BUF/Mna rats.
Mamm Genome. 1996 Jul;7(7):505-8.

Amo H, Saito M, Nagao S, Yagiu S, Takahashi H, Morita H, Morita TM, Matsuyama M.
Genetic regulation of slowly progressing mild muscle atrophy in fast-twitch muscles of BUF/Mna rats.
Muscle Nerve. 1997 Oct;20(10):1258-63

Murayama S, Yagyu S, Higo K, Ye C, Mizuno T, Oyabu A, Ito M, Morita H, Maeda K, Serikawa T, Matsuyama M.
A genetic locus susceptible to the overt proteinuria in BUF/Mna rat.
Mamm Genome. 1998 Nov;9(11):886-8

Akiyama K et al
Actin-related protein 3 (Arp3) is mutated in proteinuric BUF/Mna rats
Mamm Genome 2008
Additional strain information BUF   

 
 
 
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