In publishing, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others 骨格筋萎縮
Control Strain
Marker Strain
Gene Affected
Foxn1: forkhead box N1
Origin
BUF/Mna, NN1H-Rnu/Rnu
Strain characteristics
spontaneous development of epithelial thymoma, nephrotic syndrome
Breeding Conditions
BUF/Mna-Rnu/+ × BUF/Mna-Rnu/Rnu. Sib mating.
Genotyping
References
Matsuyama M, Yamada C, Kojima A.
Possible single dosage effects of the nude gene: suppression of spontaneous development of thymoma and nephropathy in BUF/Mna-rnu/+ rats.
Jpn J Cancer Res. 78(1):40-4, 1987.
Matsuyama, M., et al.: in "Immune-Deficient Animals in Experimental Medicine, eds. B. Wu, J. Zheng, Karger, New York, 1989