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體外受精IVF與生殖工程   實驗動物特殊飼料   日本IAR實驗動物   美國 The Jackson Lab   美國 Taconic Biosciences   近交系小鼠 Inbred Mouse   免疫缺陷小鼠 Immunodeficiency   疾病模式大鼠   疾病模式小鼠   各種實驗動物   Tg實驗動物   遠交系大鼠 Outbred Rat   閉鎖群 Closed Colony   日本實驗大鼠、小鼠   疾病模式動物     Preservation Status:   Embryo        Sperm       Living Animals     Coat Color  cincinnamon Inbred Generations  F5 Usage Restrictions  In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature(s) designated by the DEPOSITOR is requested. Genetic Status   Inbred  Segregating   Congenic   Consomic   Recombinant   Coisogenic   Spont. Mutant  Transgene  Ind. Mutant  Category Other  Comercial Availability     Research Category   Diabetes Obesity  Neurobiology  Ophthalmology   Dentistry  Cardio Hypertension  Cancer  Metabolism  Otorhinology  Immunology  Infectious  Osteosis   Internal Organ  Dermatology   Reproduction   Development  Behavior  Hematology  Urology   Pharmacology  Research Area Others   Control Strain  Marker Strain Gene Affected ATP7B: ATPase, Cu++ transporting, beta polypeptide Origin   Strain characteristics   Breeding Conditions Good breeding performance. Genotyping   References Meng Y, Miyoshi I, Hirabayashi M, Su M, Mototani Y, Okamura T, Terada K, Ueda M, Enomoto K, Sugiyama T, Kasai N. Restoration of copper metabolism and rescue of hepatic abnormalities in LEC rats, an animal model of Wilson disease, by expression of human ATP7B gene. Biochim Biophys Acta. 5;1690(3):208-19, 2004. Additional strain information LEC

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