The recipient of BIOLOGICAL RESOUCE shall obtain a prior written consent on use of it from the DEPOSITOR for one year from the deposited date forth. After that, the recipient is requested to cite in the following literature designated by the DEPOSITOR.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
lacZ: beta-galactosidase, E. coli
Origin
This strain was established at Jichi Medical School.
Strain characteristics
This transgenic strain expresses LacZ gene ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscle. The strain NBRP No.0280 (line30) is more strongly stained by X-gal staining.
Breeding Conditions
Good breeding performance.
Genotyping
References
Takahashi M, Hakamata Y, Murakami T, Takeda S, Kaneko T, Takeuchi K, Takahashi R, Ueda M, Kobayashi E.
Establishment of lacZ-transgenic rats: a tool for regenerative research in myocardium.
Biochem Biophys Res Commun. 2003 Jun 13;305(4):904-8.
Takahashi M, Hakamata Y, Takeuchi K, Kobayashi E.
Effects of different fixatives on beta-galactosidase activity.
J Histochem Cytochem. 2003 Apr;51(4):553-4.