In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature designated by the DEPOSITOR is requested.
Danober L., Deransart C., Depaulis A., Vergnes M., Marescaux C. Pathophysiological mechanisms of genetic absence epilepsy in the rat. Prog. Neurobiol. 1998 May; 55 (1): 27-57.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
Origin
Thirty per cent of the Wistar rats from the initial breeding colony in their laboratory in Strasbourg presented spontaneous spike and wave discharges (SWDs) which were bilateral and synchronous over the cerebral cortex. A strain in which all animals displayed SWDs was selected after several generations by selecting breeders with SWDs.
Strain characteristics
Breeding Conditions
Good breeding performance.
Genotyping
References
Danober L, Deransart C, Depaulis A, Vergnes M, Marescaux C.
Pathophysiological mechanisms of genetic absence epilepsy in the rat.
Prog Neurobiol. 55(1):27-57, 1998.
Rudolf G, Thérèse Bihoreau M, F Godfrey R, P Wilder S, D Cox R, Lathrop M, Marescaux C, Gauguier D.
Polygenic control of idiopathic generalized epilepsy phenotypes in the genetic absence rats from Strasbourg (GAERS).
Epilepsia. 45(4):301-8, 2004.
Embryo 
Sperm 
