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Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
Origin
The rat showed abnormal hair texture and mammary gland hypoplasia was occurred in the WTC.ZI-Atrnzi colony at the National Cancer Center Research Institute in 1998. After elimination of zi allele, this strain has been maintained by sib mating and transferred to Kyoto Univ. in April 2002.
Strain characteristics
Homozygous mutants show sparse fur, which is most prominent at 3–4 weeks of age, and small body size. Swh (Sparse and wavy) locus was mapped on Chr 17.
Breeding Conditions
Both, male and female rats are fertile. However heterozygous female and homozygous male are mated.
Genotyping
References
Kuramoto T, Morimura K, Nomoto T, Namiki C, Hamada S, Fukushima S, Sugimura T, Serikawa T, Ushijima T.
Sparse and wavy hair: a new model for hypoplasia of hair follicle and mammary glands on rat chromosome 17.
J Hered. 2005 Jul-Aug;96(4):339-45.