In publishing, the references designated by the DEPOSITOR are requested to be cited.
Genetic Status
Inbred
Segregating
Congenic
Consomic
Recombinant
Coisogenic
Spont. Mutant
Transgene
Ind. Mutant
Category Other
Comercial Availability
Research Category
Diabetes Obesity
Neurobiology
Ophthalmology
Dentistry
Cardio Hypertension
Cancer
Metabolism
Otorhinology
Immunology
Infectious
Osteosis
Internal Organ
Dermatology
Reproduction
Development
Behavior
Hematology
Urology
Pharmacology
Research Area Others
Control Strain
Marker Strain
Gene Affected
luc: luciferase, firefly
Origin
This strain was established at Jichi Medical School. This transgenic rat was originated from LEW (RT1l) strain purchased from Charles River Japan.
Strain characteristics
This strain expresses luciferase ubiquitously driven by the gene trap ROSA 26 promoter. The strength of the transgene expression of this strain is poorer than that of luc11 (NBRP No.0299). The expression of transgene is ubiquitous except for bone-marrow cell and blood.
Breeding Conditions
Good breeding performance.
Genotyping
References
Hakamata Y, Murakami T, Kobayashi E.
"Firefly rats" as an organ/cellular source for long-term in vivo bioluminescent imaging.
Transplantation. 27;81(8):1179-84, 2006.