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  • Pressure or volume-cycled
  • Pressure cycling prevents hyperinflation of tiny animal lungs
  • External lung pressure monitoring in pressure-cycling mode
  • Wide tidal volume and rate range
  • Internal air pump

   Data Sheet

The Small Animal Ventilator, suitable for a mouse or guinea pig, operates as either a volume or pressure-cycled ventilator, meaning that it dispenses a designated volume of air with each breath or it ventilates until a designated lung pressure is reached. Pressure-cycled ventilation prevents hyper-inflation of small animal lungs. When the ventilator operates in Volume mode, it dispenses a known airflow into the lungs for a set inspiratory time to generate the desired tidal volumes. The three controls – respiratory rate, inspiratory time and flow rate – allow for accuracy and extraordinary flexibility over a wide range of volumes, breaths-per-minute and I/E ratios. When the ventilator operates in Pressure mode, a built-in solid-state transducer monitors airway pressure. Simply set the desired end-inspiratory pressure. During inspiration, airflow is introduced into the lungs until this pressure is reached, at which point inspiration is terminated. This mode is especially useful for tiny animals, where hyperinflation of the lungs is a danger. An output voltage corresponding to airway pressure is provided for external monitoring or recording.

The SAR-830/AP ventilator comes with an internal air pump, but it can also connect with an external pressurized air or gas source for operation. This can be any suitable breathing gas within the required pressure range or the output from an anesthesia machine. It is compatible with inhalation anesthetics and oxygen. This unit may be expanded to ventilate larger animals or multiple small animals simultaneously by adding external valve assemblies. A metered flow source is required for each external valve assembly. These valves are available for animals ranging in size from mice to large dogs.

Specification

Respiratory rate range 5-200 breaths/min
Tidal Volume range * 0.2 - 35ml
Inspiration time range 0-5.00 seconds
Inspiratory flow rate range 0-1000 ml/min
Pressure control range 0-50.0 cmH2O
Analog rate output voltage 10mV/breath/min
Analog pressure output voltage 50mV/cmH2O
Logic Sync Out voltage 5V (TTL)
Power requirements 120/240VAC, selectable
Input pressure range ** 3-20 psi
Dimensions 9Wx5.5Hx9D in(23x14x23 cm)

*Using internal valves. External valve assemblies available for larger animals.
** No pressure source required for model SAR


Citations

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Hibert, P., & Prunier-Mirebeau, D. (2013). Apolipoprotein AI Is a Potential Mediator of Remote Ischemic Preconditioning. PloS one. Retrieved from http://dx.plos.org/10.1371/journal.pone.0077211

Hoffmann, U. (2012). Glucose modulation of spreading depression susceptibility. Journal of Cerebral  …. Retrieved from http://www.nature.com/jcbfm/journal/vaop/ncurrent/full/jcbfm2012132a.html

Hoffmann, U., & Sukhotinsky, I. (2012). Increased glucose availability does not restore prolonged spreading depression durations in hypotensive rats without brain injury. Experimental  …. Retrieved from http://www.sciencedirect.com/science/article/pii/S0014488612003226

Huang, C., Han, X., Li, X., & Lam, E. (2012). Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury. The Journal of  …. Retrieved from http://www.jneurosci.org/content/32/10/3333.short

Jeanneteau, J., & Hibert, P. (2012). Microparticle release in remote ischemic conditioning mechanism. American Journal of …. Retrieved from http://ajpheart.physiology.org/content/303/7/H871.short

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