DAM80細胞外生物放大器, 附主動式探針
Extracellular Amplifier with Active Probe
型號： SYS-DAM80

• 低噪音細胞外生物放大器。
• 採用高品質組件製成，確保最小化內在(散粒)雜訊。
• 電池供電，以消除線路噪音。
• 手持式。
• 可安裝於機架上。
• 包含低噪音Headstage。
• AC放大。(AC amplification only)

特色

WPI的 DAM系列放大器是知名的細胞外電位放大業內標準。此款電池式生物放大器的緊湊設計，讓研究人員放置在離待測物更近的位置，有效減少過長導線造成的噪音。每個放大器均搭配可調式高/低濾波器，和一 個位置控制(position control)用於抵消紀錄時產生的偏移電位。模式選擇功能提供的附加功能，對於特定應用上十分有用。內含啟動套組，如下圖所示：

電流生成

閘或手動電流生成，用於病理標記、離子導入或細胞刺激。

遠端操控主動式Headstage

DAM80為AC放大器，特別附有一個非常低噪音干擾headstage探針，可被安裝在顯微操縱器上用於：近距離大腦皮質紀錄、自高阻抗玻璃或金屬微電極的細胞外紀錄，亦提供一個閘電流用於組織標記。

 可攜帶性

DAM系列放大器可在任何桌面上，作為一個獨立裝置使用，或是使用選配的安裝夾具零件，方便的將其安裝在工作區內。此外，標準型裝置機架可使用機架安裝套組(#3484)安裝2組放大器。多種掛勾配件，可搭配您的需求選購。

 規格

搭配各式選配，可有多種應用。以下您可以看到2種設置。

金屬電極的差分應用

在此配置中，金屬電極搭配差分放大器使用，下圖使用DAM80，但是您也可以簡單換成DAM50(搭配#5489)、ISO-DAM8A(搭配#74040)或ISO-80。

Mutliple applications are available with a variety of options. Here you can see two setups.

Differential Applications for Metal Electrodes

In this setup, metal electrodes are used with a differential amplifier. In this setup, a DAM80 is shown, but you could easily substitute a DAM50 (with 5489), ISO-DAM8A (with 74040) or ISO-80.

利用玻璃為電極的細胞外應用

在罕見情形下當使用細胞外放大器搭配玻璃，你可以採用下圖所示配置。在此設置中採用DAM80，但您也可以簡單的替換成ISO-DAM8A(搭配#74040)或ISO-80。同樣的，此設置採用#2505握柄 (1/4"-6.3mm)，但是若您的顯微操縱器較小，可能需要使用#5444握柄(3/16"-4.8mm)。圖中配置採用MEH7W-10，但是任何玻璃尺寸的MEH7W均可使用。(MEH7W-10是1.0mm玻璃、MEH7W-12為1.2mm玻璃、MEH7W-15為1.5mm玻璃、MEH7W-20為2.0mm玻璃) 圖中的EP2用於接地。

單端型應用時，在黑色連接器插座上的#2033線纜適配器可連接至#3294電纜。尖端依您的需求而定。圖中建議使用#TIP1TW1。注意，下圖未顯示出玻璃。

Extracellular Applications Utilizing Glass Microelectrodes

For rare instances when using extracellular amplifiers with glass, you could use the setup shown below. In this setup, a DAM80 is shown, but you could easily substitute an ISO-DAM8A (with 74040) or ISO-80. Likewise, this setup shows the 2505 handle (1/4" - 6.3mm), but if you have a smaller micromanipulator, you may need the 5444 handle (3/16" - 4.8mm). In this illustration, MEH7W-10 is used, but any glass-size MEH7W could be used. (MEH7W-10 is 1.0mm glass, MEH7W-12 is 1.2mm glass, MEH7W-15 is 1.5mm glass and MEH7W-20 is 2.0mm glass.) EP2 is used for grounding in the illustration.

For single-ended applications, however, a 2033 wire adapter on the black connector socket can be connected to the 3294 cable. The tip used depends on your specific needs. In the illustration, TIP1TW1 was suggested. NOTE that the glass is not shown in the illustration below.

Features

WPI’s DAM series amplifier’s are well known as a standard of the industry for extracellular potential amplification. These battery powered bio-amplifiers are designed with a compact chassis profile that enables the user to locate the unit closer to the preparation and thereby minimize long lead lengths which contribute to noise. Each amplifier is equipped with selectable high and low filters, and a position control to offset galvanic potentials which may develop during recording. A choice of models offer additional features that are useful for certain applications. The startup kit (included) is shown in the image below.

Current Generation

Gated or manual current generation for histological marking, iontophoresis, or cell stimulation.

Remote Active Headstage

DAM80, an AC amplifier only, features a very low noise headstage probe which can be mounted in micromanipulators for up-close cortical recording, for extracellular recording from high impedance glass or metal microelectrodes. Also provides a gated current for tissue marking.

Portability

DAM series amplifiers can be used as standalone units on any tabletop, or use optional clamp-mounting hardware to locate them conveniently within the work area. Alternatively, a pair of amplifiers can be mounted into a standard equipment rack with a rack mount kit (#3484). A variety of hook up accessories are available to configure your application